Optimization of integration of jaw bone tissue by cellular structures made of titanium impregnated with ascorbic acid

Abstract

The article presents a study on improving the efficiency of osseointegration processes in the plastic of jaw defects by using ascorbic acid in an experiment.
 Structured implants with cells of 250 microns, obtained by growing on the Realizer SLM 50 installation, were implanted in guinea pigs in the lower jaw area (observation period of 1 month). For this purpose, 2 groups were formed: the main one — 5 animals and the comparison group — 3 animals. Ascorbic acid was a stimulant for the growth of connective and bone tissue. A method of introducing it into the implant cells has been developed. Studies were carried out on Altami MET-5D, a universal metallographic microscope used to work in reflected light at a magnification of 10 times.
 As a result of the study, the IV degree of fixation prevailed in the main group (33.3±0.2%), the IV degree of fixation was also revealed in the comparison group (25±0.2%). Using an inductor (Vit. C) coarse-fibrous bone tissue was formed in implants with cells measuring 850 microns (term of 1 month), and in the absence of a modulator, connective tissue and cartilaginous tissue, penetrated by a network of small vessels, prevailed at the same time.
 It is concluded that implants with a face-centered cubic crystal lattice structure have sufficiently high integration properties. At the same time, the use of vitamin C as a stimulant significantly increases the growth and integration of both connective and various types of bone tissue.