Abstract
Hydroxyapatite [Ca10(PO4)6(OH)2] (HAp) has been regarded as a bone mineral, which acts as a grafting material due to its similar chemical composition with natural bones. HAp is thermodynamically stable at physiological pH and actively takes part in bone bonding. This property led has lead to HAp being widely used for rapid bone repair. HAp is derived from natural bio wastes such as fish scale which is the most definite standard source of both organic and inorganic constituents like collagen and hydroxyapatite. Titanium biomimetic method with the immersion of Stimulated Body Fluid solution were also used widely used for the precipitation of hydroxyapatite synthetically. Hence scales of Sardinella longiceps and titanium are chosen to be the essential source for the isolation of hydroxyapatite (HAp) in this current study. X-Ray Diffraction, Fourier-Transform Infrared spectrometry, Scanning Electron Microscopy confirms the phase, structural integrity and size of isolated HAp. Biocompatibility and calcium deposit assay with osteoblast cell line demonstrates the non-toxicity and efficiency of calcium deposits by HAp scales rather than synthetically derived Titanium mediated HAp. Hydroxyapatite can be doped with bactericidal silver nitrate and a biopolymer, bioadsorbable chitosan for the controlled release, targeted delivery, and corrosion resistance.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
