Abstract
Purpose: Murine models of osteoarthritis (OA) are commonly used to discover new pathways involved in OA and histologic evaluation is the gold standard for determination of OA severity. The primary objective of this study was to determine the ramifications of applying the Articular Cartilage Structure (ACS) or Osteoarthritis Research Society International (OARSI) grading scheme to either a single mid-coronal section or multiple sections of the stifle (knee joint) in two murine models: young mice with surgically-induced (destabilization of the medial meniscus/DMM) OA and older mice with naturally occurring OA.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
