Abstract
Optimization of ion-exchange high-performance liquid chromatography with refractive index detection of major carboxylic acids, sugars, glycerol and ethanol in wines was carried out by using a super-modified simplex method and a modelling response surface method. A modification of the CRF criterion (chromatographic response function) for selectivity optimization was used, including different weighting factors for each pair of peaks (VCP criterion; variable coefficient parameters).
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Paper version not known
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
