Optimization and stabilization of gold nanoparticles by using herbal plant extract with microwave heating.

Akbar Yasmin,Shanmugam Rajeshkumar,Kumaraswamy Ramesh

doi:10.1186/s40580-014-0012-8

Abstract

In this study, we have synthesized the gold nanoparticles by using Hibiscus rosa-sinensis, a medicinal plant. The gold nanoparticles were synthesized rapidly by the involvement of microwave heating. By changing of plant extract concentration, gold solution concentration, microwave heating time and power of microwave heating the optimized condition was identified. The surface Plasmon resonance found at 520 nm confirmed the gold nanoparticles synthesis. The spherical sized nanoparticles in the size range of 16–30 nm were confirmed by Transmission Electron Microscope (TEM). The stability of the nanoparticles is very well proved in the invitro stability tests. The biochemical like alkaloids and flavonoids play a vital role in the nanoparticles synthesis was identified using the Fourier Transform Infrared Spectroscopy (FTIR). Combining the phytochemical and microwave heating, the rapid synthesis of gold nanoparticles is the novel process for the medically applicable gold nanoparticles production.

Highlights

Nanotechnology is mainly concerned with the synthesis of nanoparticles of variable sizes, shapes, chemical compositions and controlled dispersity and their potential use for biomedical applications [1]
The biochemical like alkaloids and flavonoids play a vital role in the nanoparticles synthesis was identified using the Fourier Transform Infrared Spectroscopy (FTIR)
As an alternative to toxic and expensive physical methods for nanoparticles fabrication, using microorganisms, plants and algae will help a lot to synthesize the materials in the nano range and in addition, the toxicity of the by-product would be lesser than the other synthetic methods [2,3,4]

Summary

Introduction

Nanotechnology is mainly concerned with the synthesis of nanoparticles of variable sizes, shapes, chemical compositions and controlled dispersity and their potential use for biomedical applications [1]. Chemical and physical methods may successfully produce pure, well defined nanoparticles, these are quite expensive and potentially dangerous to the environment. As an alternative to toxic and expensive physical methods for nanoparticles fabrication, using microorganisms, plants and algae will help a lot to synthesize the materials in the nano range and in addition, the toxicity of the by-product would be lesser than the other synthetic methods [2,3,4]. The cause is chemicals which will be used in nanoparticles synthesis will get degraded by the enzymatic substances which are produced by the microbes during the time of growth. Using the biological organisms such as micro organisms [6], plant extract or plant biomass could be an alternative to chemical and physical methods for the production of nanoparticles [7,8]

Methods

Results

Conclusion