Abstract

<p><em>One way to maintain healthy skin is through skincare that incorporates natural ingredient scrubs. Free radicals contribute to the onset of cell damage associated with skin aging. Mareme leaves (Glochidion arborescens Blume.) contain antioxidants that can inhibit the reaction of free radicals in the body. The purpose of this study was to incorporate the ethanol extract of mareme leaves into a scrub formulation containing cornflour and rice flour. This study begins with a phytochemical screen, followed by TLC analysis of antioxidant activity using the DPPH-free radical scavenging test, evaluation of cream scrubs, and ANOVA data analysis. According to research, the ethanol extract of mareme leaves possesses a significant antioxidant activity of 4.32 parts per million. The effect of variations in cornstarch and rice flour on the formulation of cream scrubs was determined through organoleptic testing of all semisolid preparations, with an emphasis on different smells and colors; all formulas have a pH suitable for the skin of 4.5-8, and each formula contains less than 50 ppm of potent antioxidant activity. A significant value of 0.05 indicates that there is a significant difference between the four formulas based on the ANOVA test comparing IC<sub>50</sub> values between preparations. It has to do with the addition of cornstarch scrub and rice flour to each formula. It can be concluded that the ethanol extract of mareme leaves (Glochidion arborescens Blume) possesses exceptional antioxidant activity. According to the stability test, the best formula for cream scrub preparations is formula 3.</em><em></em></p>

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