Optimal time of phototherapy for newborns whose total bilirubin ranges from 75 th to 95th percentile in the hour - specific serum bilirubin nomogram

Abstract

Objective To study the optimal time of phototherapy for newborns (gestational age≥36 weeks and birth weight≥2500 g) whose total bilirubin ranges from 75th to 95th percentile in the hour - specific serum bilirubin nomogram.Methods The hour - specific serum bilirubin nomogram recommended by America in 2004 was used in this study.Newborns total serum bilirubin (TSB) values from 75th to 95th percentile were divided into 2 groups based on high -risk factors of jaundice inside 72 hours after birth:the observed group with high - risk factors of jaundice and the CK group without them.The number of TSB of the newborns TSB beyond 95th percentile outside 72 h after birth was researched in the two groups.Results Before discharge,total serum bilirubin (TSB) values of 12.8％ (5/39) infants were in the high risk zone ( ＞95th percentile) in the CK group and of 32.2％ (10/31) were in that zone in the observed group.The difference was significant ( x2 =3.876,P ＜ 0.05 ).Conclusions Phototherapy should begin inside 72 hours after birth for the newborns with high - risk factors of jaundice and (TSB) values from 75 th to 95 th percentile,and the primary diseases should be treated actively. Key words: Neonatal; Hour - specific serum bilirubin; High - risk factors