Abstract
Background The analysis of the atherogenic potential of the lipid profile for biomarkers, such as the TG/HDL-c ratio, predicts cardiovascular risk better than isolated lipids. Objective To identify the TG/HDL-c cutoff points for multiple risks (hypertension, Diabetes Mellitus, obesity) and to evaluate the association between sociodemographic, clinical, laboratory, anthropometric, and life habit variables and the TG/HDL-c ratio in hypertensive and/or diabetic individuals in the context of Primary Health Care. Methods This was a cross-sectional study with 833 hypertensive and/or [...]
Highlights
Cardiovascular diseases (CVD) are one of the most important public health problems in the world and one of the main causes of prolonged hospitalization and health expenditures in Brazil.[1,2] Among cardiovascular diseases (CVD), coronary artery disease (CAD) stands out as the leading cause of death in Brazil[3,4] and worldwide.[3]Dyslipidemias are related to the development of atherosclerosis and, CAD.[5]
The lipoproteins (HDL-c) and low densities (LDL-c)/HDL-c ratio is a classic index for predicting AD, but the TG/HDL-c ratio is the best predictor for acute myocardial infarction, associated with insulin resistance and metabolic syndrome.[5]
The present study presents as strengths the achievement of the cutoff values of the TG/HDL-c ratio by Receiver Operating Characteristic (ROC) analysis with a more satisfactory and effective result to discriminate cardiovascular risk (CVR); having been conducted with adults and the elderly – a population with a tendency to present more CVR-factors, and at the level of Primary Health Care (PHC) – aninstance in which hypertensive and diabetic patients are treated
Summary
Cardiovascular diseases (CVD) are one of the most important public health problems in the world and one of the main causes of prolonged hospitalization and health expenditures in Brazil.[1,2] Among CVD, coronary artery disease (CAD) stands out as the leading cause of death in Brazil[3,4] and worldwide.[3]Dyslipidemias are related to the development of atherosclerosis and, CAD.[5]. Is important to prevent CVD,[1,5,6] define therapy[6] and reduce complications[1] and mortality.[5] CVD prevention is a public health priority, especially in high-risk individuals, such as those diagnosed with arterial hypertension (AH) or Diabetes Mellitus (DM). The analysis of the atherogenic potential of the lipid profile for biomarkers, such as the TG/HDL-c ratio, predicts cardiovascular risk better than isolated lipids. Objective: To identify the TG/HDL-c cutoff points for multiple risks (hypertension, Diabetes Mellitus, obesity) and to evaluate the association between sociodemographic, clinical, laboratory, anthropometric, and life habit variables and the TG/HDL-c ratio in hypertensive and/or diabetic individuals in the context of Primary Health Care.
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