Abstract

This paper reports the principle and applications of the combination technique of optical trapping and Raman spectroscopy for real-time analysis of single living cells. We demonstrate that the information of each substance inside a captured cell can be retrieved by the Raman spectrum of the cell. The effect of alcohol solution on single human Red Blood Cell (RBC) is investigated using near-infrared laser tweezers Raman spectroscopy (LTRS). The significant difference between the spectrum of fresh RBC and the spectrum of RBC exposed to alcohol is observed due to the degradation of RBC. We also present the preliminary study result on the diagnosis of colorectal cancer using LTRS system.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.