Abstract

1-Ferrocenylethanol and its analogues were completely resolved into their enantiomers by liquid chromatography on a polyamide column using aqueous cyclomaltohexaose (α-cyclodextrin, αCD) as the mobile phase. The stability constants (K c) for the inclusion complexes of αCD with each enantiomer of 1-ferrocenylethanol, determined by liquid chromatography with various concentrations of αCD, were ▪ for ( S)-ferrocenylethanol and ▪ for the ( R) isomer. The temperature dependence of the resolution has been studied.

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