Abstract
Background. To evaluate the differences in the corneal higher-order aberrations (HOAs) and optical quality of the ptosis eyes compared with the normal fellow eyes in the unilateral congenital ptosis patients. Methods. A matched case-control study was performed in 17 pairs of eyes in 17 unilateral congenital ptosis patients. The ptosis eye was enrolled in the ptosis group while the normal fellow eye was enrolled in the normal group. The HOAs obtained from Pentacam HR and the optical quality parameters obtained from Optical Quality Analysis System (OQAS) were compared between the two groups. Results. There were significant differences in a vertical coma and vertical trefoil on the anterior corneal surface between the ptosis group and the normal group p < 0.05 . The OQAS parameters in the ptosis group were significantly different from those in the normal group p < 0.05 . The vertical fissure height (VFH) showed a significant correlation with the total HOAs, 3rd HOAs, and vertical coma on the anterior corneal surface p < 0.05 . Conclusions. Compared with the normal fellow eyes, the ptosis eyes showed significantly degraded optical quality. The eyelid position was important for the changes of corneal HOAs in the ptosis eyes. The reasons for the discrepancy of the OQAS parameters between the ptosis eyes and normal fellow eyes were multiple.
Highlights
Congenital ptosis is a rare eyelid disease characterized by lower positioning of the upper eyelid presenting at birth or within the first year of life
We investigated the differences in the corneal higher-order aberrations (HOAs) and Optical Quality Analysis System (OQAS) parameters between the ptosis eyes and the normal fellow eyes
Our results showed there was a significant difference in best-corrected visual acuity (BCVA) between the two groups, but there was no significant difference in spherical equivalent refraction
Summary
Congenital ptosis is a rare eyelid disease characterized by lower positioning of the upper eyelid presenting at birth or within the first year of life. It may be either unilateral or bilateral. To evaluate the differences in the corneal higher-order aberrations (HOAs) and optical quality of the ptosis eyes compared with the normal fellow eyes in the unilateral congenital ptosis patients. Ere were significant differences in a vertical coma and vertical trefoil on the anterior corneal surface between the ptosis group and the normal group (p < 0.05). Compared with the normal fellow eyes, the ptosis eyes showed significantly degraded optical quality. Compared with the normal fellow eyes, the ptosis eyes showed significantly degraded optical quality. e eyelid position was important for the changes of corneal HOAs in the ptosis eyes. e reasons for the discrepancy of the OQAS parameters between the ptosis eyes and normal fellow eyes were multiple
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