Abstract
We have successfully developed and manufactured a three-layered scattering agent-embedded optical phantom in order to mimic the structural and optical properties of the human skin. Characterization is done for the optical phantom. The widths of the individual layers can be controlled within +/-10% of the designed thickness. The refractive indices, scattering and absorption coefficients are close to the human skin. The scattering agents in the optical phantom act as point sources which can be used to measure point spread function (PSF). Such a device can be useful for applications that require an accurate optical model for human skin evaluation such as Optical Coherence Tomography (OCT) and Reflectance Confocal Microscopy (RCM) in cosmetics and dermatological diagnostics.
Highlights
Optical Coherence Tomography (OCT) and Reflectance Confocal Microscopy (RCM) are 3D imaging technologies which can be used in cosmetic and medical applications
Our objective is to develop a multi-layer optical phantom that will demonstrate optical properties that are comparable to the skin
Optical phantoms are very useful for applications that require a very accurate optical model for human skins evaluation and they can be helpful in clinical settings for quality control
Summary
OCT and RCM are 3D imaging technologies which can be used in cosmetic and medical applications. In order to develop confocal imaging systems, optical phantom are used either to develop, optimize or test the optical pathways, or to fine tune the image processing algorithms. These optical phantoms should mimics the optical properties of the skin, which means having three different layers with different optical refractive indexes. Our objective is to develop a multi-layer optical phantom that will demonstrate optical properties that are comparable to the skin Developing such a phantom will allow to evaluate the performance of confocal imaging systems for in vivo skin imaging and to improve image processing of data acquired from those systems
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