Optical measurement of skin temperature in MR-HIFU

Daniel Yang,David Kinnaird,Karun Sharma,Avinash Eranki,Peter Kim,Haydar Celik,Doug Wackerle,Harry Kim,Matthew Oetgen,Aerang Kim,Pavel Yarmolenko

doi:10.1186/2050-5736-3-s1-p81

Abstract

MR-guided high-intensity focused ultrasound (MR-HIFU) treatments may cause skin heating in the vicinity of the treatment site. Current MR thermometry methods do not provide reliable measurements of skin temperature either during the sonication or during the cool-down periods between sonications. These technical challenges require additional pauses to decrease the likelihood of skin burns, thus impacting treatment duration. Therefore, quantitative, accurate, and rapid techniques are needed to measure surface skin temperature during HIFU treatment. This study aims to develop an optical method that detects temperature changes at the skin surface to maintain a safe skin temperature during treatment and to reduce pauses between sonications.

Highlights

Background/introduction MR-guided high-intensity focused ultrasound (MRHIFU) treatments may cause skin heating in the vicinity of the treatment site
This study aims to develop an optical method that detects temperature changes at the skin surface to maintain a safe skin temperature during treatment and to reduce pauses between sonications
Chiral nematic liquid crystal slurry (LCR Hallcrest, LLC, Glenview, IL, #09-NSL33), which displays a change in reflected light color between 25-30°C was mixed with 0.4% w/v agarose gel at 80-85°C to create a 4 mL mixture of 10% liquid crystal slurry

Summary

Introduction

Background/introduction MR-guided high-intensity focused ultrasound (MRHIFU) treatments may cause skin heating in the vicinity of the treatment site. Current MR thermometry methods do not provide reliable measurements of skin temperature either during the sonication or during the cooldown periods between sonications. These technical challenges require additional pauses to decrease the likelihood of skin burns, impacting treatment duration. Quantitative, accurate, and rapid techniques are needed to measure surface skin temperature during HIFU treatment. This study aims to develop an optical method that detects temperature changes at the skin surface to maintain a safe skin temperature during treatment and to reduce pauses between sonications

Objectives

Methods

Results