Abstract
In this paper we study electromagnetic forces induced on DNA and DNA-like helices by external electromagnetic waves. We consider simultaneously occurring forces and torques, interconnected and acting along the double helix axis. Since the DNA molecule has an absorption band in the ultraviolet and visible range near wavelengths λ1res=280 nm and λ2res=500 nm, we expect that it may be possible to selectively apply engineered forces to DNA molecules using appropriate illumination by light in these frequency ranges. The optical forces are simulated for DNA fragments consisting of 20 and 35 turns. Fragments of this length are convenient for direct sequencing and subsequent use in experiments and in practice. It is shown that repulsion forces can arise between the strands of the double DNA-like helix in the field of external electromagnetic waves. Such forces are characteristic of a DNA-like helix with its specific pitch angle and are not inherent in double helices with more straightened or more compressed turns. These repulsion forces, acting along the entire helix, both for electric charges and for electric currents, can lead to damage and rupture of the strands in the double helix. In addition, there can also exist forces and moments of forces directed along the helix axis, which simultaneously stretch and unwind a double helix. The double helix equilibrium under the action of optical forces is also of interest from another point of view, i.e., for optimizing the structure of artificial magnetics and bianisotropic metamaterials for applications in all frequency ranges.
Highlights
This article is based on research carried out in recent years on the effects of electromagnetic radiation on a DNA molecule
We study electromagnetic forces induced in DNA molecules by external electromagnetic waves
This paper considers a double DNA-like helix in the field of the incident electromagnetic wave, which creates a half-wave resonance in the helical strands
Summary
This article is based on research carried out in recent years on the effects of electromagnetic radiation on a DNA molecule. To analyze mechanical forces exerted on DNA helices by incident light and the danger of “improper” helix unwinding and strands rupture, we can use methods of classical electrodynamics, considering effective electric current existing in a double helix. Whereas the article by Semchenko et al [44] studies a two-fold symmetrical double stranded helix, paper [45] is devoted to an asymmetrical DNA-like helix This particular excitation state is realized when the wavelength of excitation is much longer than the length of the helical turn. The issue of the double DNA-like helix equilibrium in a linear state, as well as the danger of “improper” unwinding of the helix and strands rupture under the external wave action are considered in the framework of classical electrodynamics. These radial components of the forces describe the mutual attraction or repulsion of two helices and exist both for a symmetrical double helix and in the case of mutual shift of two helices along their common axis
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