Abstract

The optical fiber surface plasmon resonance (SPR) technology applications on DNA hybridization detection significantly improve the sensitivity, detection limit, response time and cost. Based on our recent research around optical fiber SPR DNA detection, multiple fiber optic SPR DNA detection techniques and their application areas are described in this paper. According to the applied fields, SPR-based DNA detection methods proposed by our group can be classified as the high-sensitivity DNA detection method, the temperature-compensated DNA detection method and multi-parameter DNA detection methods. These studies are important for improving traditional DNA detection technology and expanding the application of SPR technology in the field of biosensing.

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