Abstract
Genipin cross-linked gelatin hydrogels with 0.2 M sulphuric acid are radiochromic and have sufficient sensitivity for investigating doses less than 50 Gray. Because of the gelatine cross-links, these gels have sufficient strength to allow removal from the vessel container in which they were cast. Placing the gels in the same liquid that was used for preparing the gel allows the radiochemistry to the same throughout the gels and provides physical support. In this buoyancy neutral environment the gel has the same shape and the preparation vessel. This allows optical CT scanning without wall artefacts due to reflection, refraction and optical activity. A gel was irradiated to dose of 25 Gray with a 10 MV photon beam of 20 × 20 mm cross section. Full 3D optical CT scanning was performed with a Vista 10 optical cone-beam CT scanner. Central beam axis profiles and depth dose agree with diode and parallel plate ion chamber measurements. These results demonstrate that genipin cross-linked gel can be used for accurate 3D dosimetry, including surface dose measurements.
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