Abstract
Optic neuropathy is a group of diseases of the optic nerve. Using diagnostic techniques such as ophthalmoscopy and perimetry diagnosis are insufficient, as the found abnormalities are not specific for either inflammation or ischemia. Establishing the predominant factor in the pathogenesis of neuropathy is crucial in determining the method of treatment.
 The aim of the study: to investigate the features of optic nerve damage using optical coherent tomography (OCT) in optic neuropathy in the acute period.
 Materials and methods: two patients with visual impairment were examined.
 Result. Patient G. had concomitant rheumatoid arthritis with unregulated Methotrexate therapy. OCT revealed edema of the nerve fibre layer convinced of the predominance of inflammatory neuropathy (atypical neuritis). Pulse therapy with corticosteroids was prescribed, which gave a positive functional effect.
 A patient O. with pneumonia on the background of Covid-19 with a history of OST showed a decrease in the thickness of the layer of nerve fibres in the lower segment, and in the angio mode – drusen of the optic disc.
 Conclusions. Thus, the use of OCT for the diagnosis of optic neuropathies in the acute period showed that under conditions of inflammatory lesions is more characteristic of edema and an increase in the thickness of the layer of nerve fibres. In ischemic neuropathy, on the contrary, a decrease in the thickness of nerve fibres is more characteristic, which correlates in location with the localization of scotoma in the field of view.
 Therefore, the use of OCT of the optic nerve will help in understanding the pathogenesis of forms of optic neuropathy. This will help in the choice of treatment tactics
Highlights
Optic neuropathy is a group of diseases of the optic nerve
OST showed a decrease in the thickness of the layer of nerve fibres in the lower segment, which is characteristic of ischemic lesions of the optic nerve
On the contrary, according to our study, there was a decrease in the thickness of nerve fibres
Summary
Optic neuropathy is a group of diseases of the optic nerve. In the acute form, they are manifested by varying degrees of decreased visual acuity and narrowing of the visual field, disorders of the pupillary afferent reaction. According to the modern classification, among the acute neuropathies the most common are inflammatory [1, 2] and ischemic [3, 4]. This division is quite conditional, as in the nervous system inflammation and ischemia occur simultaneously, and are accompanied as secondary mechanisms of damage in traumatic [5] and toxic neuropathies [6]. Edema of the disc, which is characteristic of the acute phase, can occur in both neuritis and ischemic neuropathy [7]. The establishment of the predominant factor in the pathogenesis of neuropathy in a particular case is crucial for the appointment of a method of treatment
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
