Optical Coherence Tomography in Progressive Outer Retinal Necrosis

Abstract

<P>A 38-year-old man with human immunodeficiency virus was referred for evaluation of retinal lesions in both eyes. Optical coherence tomography was performed after dilating the pupils. Biomicroscopy of the retina showed an atypical, solitary, yellowish-white lesion in the macula of both eyes with no inflammation of the vitreous. Optical coherence tomography of the lesions showed an area of extremely low reflectivity with well-defined but irregular borders in the outer retina. The surrounding retina showed normal reflectivity and was of normal thickness. Optical coherence tomography showed selective necrosis of the outer layers due to progressive outer retinal necrosis. Optical coherence tomography may serve as a useful tool for the early diagnosis of progressive outer retinal necrosis. [<CITE>Ophthalmic Surg Lasers Imaging</CITE> 2006;37:506-507.] </P> <H4>AUTHORS</H4> <P>From the Department of Ophthalmology (RN, BDK), University of California, Irvine, California; and the L. V. Prasad Eye Institute (RN), Hyderabad, India. </P> <P>Accepted for publication August 4, 2006. </P> <P>Presented at the annual meeting of the Association for Research in Vision and Ophthalmology, May 1-5, 2005, Fort Lauderdale, Florida. </P> <P>Address reprint requests to Baruch D. Kuppermann, MD, PhD, Department of Ophthalmology, University of California–Irvine, 118 Med Surge I, Irvine, CA 92697-4375.</P>