Abstract
Background/alms: Optical coherence tomography is a new in vivo imaging tool originally developed to investigate the eye. We undertook a preliminary investigation of experimental and clinical dermatological applications.Methods: We obtained optical coherence tomography images of ethnic groups, of cutaneous changes induced by exposure to water and dimethyl sulfoxide, of corticosteroid atrophy and of acne vulgaris.Results: Optical coherence tomography was able to visualize specific structural changes in stratum corneum and viable epidermis in these diverse conditions.Conclusions: The high lateral and axial resolution of 4 urn and 7 μm, respectively, and the image quality of this prototype make optical coherence tomography a promising instrument for clinical and investigative dermatology.
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