Abstract

In this chapter, we first introduce the basic working principles of optical coherence tomography (OCT). Three types of OCT, including time-domain, spectral-domain, and swept-source OCT are discussed. Functional OCT methods, including polarization sensitive OCT (PS-OCT), spectroscopic OCT (S-OCT), optical coherence elastography (OCE), and OCT angiography (OCTA) are also described. Furthermore, recent advances in high-speed and high-resolution OCT technologies are reviewed. We also highlight several OCT applications in biomedicine, including ophthalmology, cardiovascular imaging, and oncology. Continuous innovations and further developments in the OCT field will generate long-lasting research and clinical impact in biology and medicine.

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