Abstract
Optical Coherence Tomography and Densitometry in Assessing the Effect of Corneal Collagen Cross-Linking Upon Photorefractive Ablation with Riboflavin
Highlights
Corneal thinning affects biomechanics of the cornea and its photoprotective function which has an important role in intraocular protection against external Ultraviolet (UV) irradiation [1,2]
The formation of a membrane-like structure on the ablation surface, the increased optical density and the demarcation line in the corneal stroma layers are the objective criteria for the cross-linking effect upon photorefractive ablation with riboflavin according to optical coherence tomography and corneal densitometry
To assess the effect of corneal cross-linking upon photorefractive ablation with riboflavin according to optical coherence tomography and densitometry of the cornea
Summary
Corneal thinning affects biomechanics of the cornea and its photoprotective function which has an important role in intraocular protection against external Ultraviolet (UV) irradiation [1,2]. The outcomes of modern corneal photorefractive surgeries demonstrate that most of these procedures result in corneal thinning which can cause corneal ectasia. This complication occurs more frequently after laser in situ keratomileusis (LASIK) or femtosecond laser in situ keratomeluses (FemtoLASIK). Flap creation reduces corneal biomechanical strength by 15-35% and this range results from individual characteristics of flap size and thickness. Photorefractive ablation as a second step of LASIK provides even more profound decrease in corneal strength. The higher is ametropia degree, the greater the decrease in corneal strength is [3,4,5]
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