Abstract
We analysed the imaging findings of macular telangiectasia (MacTel) type 2 in Korea using spectral domain optical coherence tomography (SD-OCT) and investigated their relationship with visual acuity and clinical stages. A retrospective multicentre cross-sectional study was conducted in six tertiary hospitals in Korea and included 129 patients. We analysed all the SD-OCT images encompassing the macular area. Hyporeflective cavities (77.7%) were the most frequently detected abnormalities in SD-OCT. Disruption of the external limiting membrane, ellipsoid zone, and interdigitation zone were found in 67 (40.4%), 87 (52.4%), and 94 eyes (56.6%), respectively. Four eyes (2.4%) had lamellar macular hole, and five eyes (3.0%) full-thickness macular hole. Neovascularisation, either subretinal or intraretinal, was found in 14 eyes (8.4%). Eyes with outer retinal hyperreflective band disruption had lower visual acuity than those without them. The presented characteristic clinical features of OCT in MacTel type 2 can not only aid in differentiating this disease from others but are also helpful for better judgement of the disease stage in daily clinical practice. Inner retinal hyporeflective cavities without outer retinal abnormalities on SD-OCT, although classified as severity scale 3, could be considered a relatively early stage in the disease process in terms of vision.
Highlights
Macular telangiectasia (MacTel) type 2 is an idiopathic bilateral disease, characterised by macular capillary network alterations and specific changes in the neurosensory retina[1]
This improved resolution can provide more precise images of the macula, and OCT has become a valuable method for diagnosing and studying macular telangiectasia (MacTel) type 2. The purpose of this multicenter study was to investigate the demographics of MacTel type 2 patients and its clinical characteristics using multimodal imaging after the introduction of Spectral domain optical coherence tomography (SD-OCT) in Korea. In this part of the Korean Macular Telangiectasia Type 2 Study, i.e., Report No 1, we focused on the SD-OCT findings of MacTel type 2 in Korean patients, while
166 eyes of 84 Korean patients with findings of MacTel type 2 were included for the analysis
Summary
Macular telangiectasia (MacTel) type 2 is an idiopathic bilateral disease, characterised by macular capillary network alterations and specific changes in the neurosensory retina[1]. Spectral domain optical coherence tomography (SD-OCT) has allowed for very-high-speed acquisition of images with high resolution This improved resolution can provide more precise images of the macula, and OCT has become a valuable method for diagnosing and studying MacTel type 2. The purpose of this multicenter study was to investigate the demographics of MacTel type 2 patients and its clinical characteristics using multimodal imaging after the introduction of SD-OCT in Korea. In this part of the Korean Macular Telangiectasia Type 2 Study, i.e., Report No 1, we focused on the SD-OCT findings of MacTel type 2 in Korean patients, while. The manifestations of MacTel type 2 using the fundus photograph (FP), fundus autofluorescence (FAF), and fluorescein angiography (FAG) will be discussed in another report, i.e., Report No 2 [Kim et al (2019) Demographic and multimodal imaging features of macular telangiectasia type 2: Korean Macular Telangiectasia Type 2 Study—Report No 2, unpublished]
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