Abstract
In this article, a theoretical design of enhanced surface plasmon resonance is proposed. The suggested sensor is composed of titanium, silver, graphene, photonic crystal, and a sensing layer. This structure is used to detect cancer cells and hemoglobin in blood plasma based on their refractive indices. Different parameters such as sensitivity and figure of merit are studied at an operating wavelength of 633 nm. The recorded sensitivity and figure of merit are 72 degrees/RIU and 346 RIU−1. The ability of the proposed sensor to detect cancer cells and blood plasma concentration will be investigated.
Highlights
Surface Plasmon Resonance (SPR) is a collective oscillation of propagated free electrons at the interface between a metallic thin sheet and a dielectric layer (Choi et al 2011; Balakrishnan et al 2016; Singh et al 2015; Singh and Black 2018)
The SPR excitation is a result of the total internal reflection (TIR)
The minimum reflected intensity confirms the excitation of the SPR
Summary
Surface Plasmon Resonance (SPR) is a collective oscillation of propagated free electrons at the interface between a metallic thin sheet and a dielectric layer (Choi et al 2011; Balakrishnan et al 2016; Singh et al 2015; Singh and Black 2018). SPR is a physical effect that allows researchers to investigate real-time biomolecular interactions This approach responds well to changes in the refractive index of the sensing material. Abdulhalim et al improved the performance of the biosensor by combining a layer of high refractive index with the metallic sheet (Shalabney and Abdulhalim 2011; Lahav et al 2008). The refractive index of the sensing substance of the PhC or the defect layer can change the resonance wavelength (Prather et al 2009; Aly et al 2008, 2021b; Abd El-Ghany et al 2020; Zaky et al 2021c, d, e; Tammam et al 2021). The optimized structure is exploited for detecting the blood plasma and different cancer cells. By examining the suggested biosensor structures’ reflectance spectra, it is feasible to calculate the various blood plasma concentrations and detect different cancer cells.
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