Abstract
The natural history of 33 optic pathway tumors (OPT) diagnosed in 227 children with neurofibromatosis type 1 (NF-1) seen in a specialty clinic was evaluated in a prospective, longitudinal study at Children’s Memorial Hospital and Northwestern University Medical School, Chicago.
Highlights
The natural history of 33 optic pathway tumors (OPT) diagnosed in 227 children with neurofibromatosis type 1 (NF-1) seen in a specialty clinic was evaluated in a prospective, longitudinal study at Children's Memorial Hospital and Northwestern University Medical School, Chicago
OPTs were found in 19% of 176 who had CT or MRI at a median age of 4.2 years
No OPT developed on later follow-up in children who had not received an MRI
Summary
The natural history of 33 optic pathway tumors (OPT) diagnosed in 227 children with neurofibromatosis type 1 (NF-1) seen in a specialty clinic was evaluated in a prospective, longitudinal study at Children's Memorial Hospital and Northwestern University Medical School, Chicago. OPTs were found in 19% of 176 who had CT or MRI at a median age of 4.2 years.
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