Abstract

Glaucoma is a common causes of blindness. The associated elevation in intra ocular pressure leads to progressive degeneration of the optic nerve and resultant structural changes with functional failure of the visual field. Since, glaucoma is asymptomatic in the early stages and the associated vision loss is irreparable, its early detection and timely medical treatment is essential to prevent further visual damage. This paper presents a novel method for glaucoma detection using digital fundus image and optical coherence tomography (OCT) image. The first section focuses on the features such as cup to disc ratio (CDR) and the inferior superior nasal temporal (ISNT) ratio which were obtained from fundus images.The above features were used for classifying the normal and glaucoma condition using back propagation neural network (BPN) and Support Vector Machine (SVM) classifiers. In the second part of the article, features such as CDR and two novel features, cup depth and retinal thickness were obtained from the OCT image. These features were evaluated by the BPN and SVM classifier. The combined features from fundus and OCT images were analyzed. The system proposed here is able to classify glaucoma automatically. The accuracy of BPN and SVM Classifiers was 90.76% and 96.92% respectively.

Highlights

  • Glaucoma is one of the common causes of blindness

  • Details about the blood vessels are not available from optical coherence tomography (OCT) images while details about the retinal thickness and the level of cupping in the form of cup depth are not found in the fundus images but all these features are important indications of glaucoma

  • Through the OCT method, in addition to cup to disc ratio (CDR), cup depth and retinal thickness values are calculated for detection of glaucoma

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Summary

Introduction

Glaucoma is one of the common causes of blindness. It causes progressive degeneration of optic nerve fibers and leads to structural changes of the optic nerve and a simultaneous functional failure of the visual field. Glaucoma is asymptomatic in the early stages and the associated vision loss is irreparable, its early detection and timely medical treatment is essential to prevent further visual damage. The first section focuses on the features such as cup to disc ratio (CDR) and the inferior superior nasal temporal (ISNT) ratio which were obtained from fundus images.The above features were used for classifying the normal and glaucoma condition using back propagation neural network (BPN) and Support Vector Machine (SVM) classifiers. In the second part of the article, features such as CDR and two novel features, cup depth and retinal thickness were obtained from the OCT image. These features were evaluated by the BPN and SVM classifier. The accuracy of BPN and SVM Classifiers was 90.76% and 96.92% respectively

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