Abstract
BackgroundThe aim of this study was to evaluate the association between optic nerve head (ONH) parameters and branch retinal vein occlusion (BRVO) using spectral domain optical coherence tomography (SD-OCT).MethodsBoth eyes of 40 patients with unilateral BRVO (mean age: 67.4 ± 11.4 years, male: female - 18:22) were enrolled in this study. Control group consisted of randomly selected single healthy eyes of 40 age and gender matched volunteers (mean age: 64.7 ± 15.4 years, male: female - 16:24). ONH parameters (including optic disc area, optic cup area, neuroretinal rim area, cup volume, rim volume, cup-disc area ratio, horizontal and vertical cup-disc ratio, average retinal nerve fiber layer) were measured by SD-OCT. Axial length (AL) of the eyes was measured by non-contact optical low coherence reflectometry. The ONH parameters of eyes with BRVO were compared with those of fellow eyes using mixed model, one-way between-groups analysis of covariance was conducted to compare the ONH parameters of affected and unaffected fellow eyes in BRVO patients with those of the control eyes keeping confounding factors, including AL, age and gender under control in the statistical analysis.ResultsNone of the investigated ONH parameters of affected BRVO eyes, unaffected fellow eyes and control eyes were statistically different after controlling for AL, age and gender.ConclusionOptic disc morphology might not be a potential anatomical predisposing factor for development of BRVO.Electronic supplementary materialThe online version of this article (doi:10.1186/s12886-015-0165-1) contains supplementary material, which is available to authorized users.
Highlights
The aim of this study was to evaluate the association between optic nerve head (ONH) parameters and branch retinal vein occlusion (BRVO) using spectral domain optical coherence tomography (SD-OCT)
It has been hypothesized that patients with Retinal vein occlusion (RVO) have smaller discs and narrow scleral canal, which may play a role in increased intraneural tissue pressure, leading to greater susceptibility of vein occlusion [7]
Forty patients with unilateral BRVO were enrolled consecutively as they were referred to the outpatient clinic of the department for examination between January 2013 and January 2015
Summary
The aim of this study was to evaluate the association between optic nerve head (ONH) parameters and branch retinal vein occlusion (BRVO) using spectral domain optical coherence tomography (SD-OCT). Branch retinal vein occlusion (BRVO) is the second most frequent retinal vascular disease with a prevalence rate of 0.3–1.1 % [1]. The major risk factors for BRVO include age, hypertension, coexisting cardiovascular diseases and retinal precursor signs (e.g., focal retinal arteriolar narrowing, severe arteriovenous nicking, smaller arterio-venous ratio) [1,2,3]. Patients with optic nerve head drusen have smaller optic disc size [4]. It has been hypothesized that patients with RVO have smaller discs and narrow scleral canal, which may play a role in increased intraneural tissue pressure, leading to greater susceptibility of vein occlusion [7]
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