Abstract

On exposure to blood, liposomes of different morphology and lipid composition attract different arrays of proteins. The mode of interaction of blood proteins with liposomes vary in quantity and conformation. These differences may explain different observed patterns in blood clearance and tissue distribution of liposomes. In this paper, an attempt is made to assess the role of serum and its components in regulating liposome recognition by isolated phagocytes of rat liver and spleen.

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