Abstract
Well-designed and conducted randomised controlled trials (RCTs) generate quality evidence that leads to improvement in surgical practice. The evidence can inform individual decision-making about the benefits and harms of a procedure, underpin national guidelines and influence policy decisions regarding investment. Although the number of surgical RCTs is substantially higher in the UK than in many other European countries, the need for more and better surgical trials is well recognised. In the UK there have recently been several major changes in research funding and infrastructure for clinical trials and these represent an important opportunity for surgeons to collaborate with clinical trials units and methodologists to design and conduct randomised surgical trials.
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