Abstract

Objectives To describe opioid prescribing practices in women undergoing elective gynecologic surgery for benign indications and determine the rate of new persistent opioid use (NPOU) among opioid-naive women. Methods Retrospective population-based cohort study using linked administrative data in Ontario supported by ICES Institute. We included opioid adult women who underwent elective gynecologic surgery between January 1st 2013 and March 31st 2018 for benign indications in Ontario, Canada. Women were included if they were opioid-naive in the year prior to surgery. Results There were 132,506 patients in our cohort. Perioperative opioid use was documented in 27,763 (21.0%) patients and NPOU was documented in 4,827 (3.65%) patients undergoing gynecologic surgery. Patients who filled an opioid prescription were more likely to develop NPOU (unadjusted OR 1.49, 95%CI 1.40-1.59, p Conclusions Women undergoing gynecologic surgeries, irrelevant of level of invasiveness, are at increased of developing NPOU when filling an opioid prescription due to their surgery. Opioids play an important role in managing post-operative pain, however, the risks and benefits of prescribing them must be carefully weighed by healthcare providers.

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