Abstract
Opioid analgesics belong to one of the basic groups in the treatment of pain. There is no class effect here, which means that each opioid used in the treatment of pain is characterized by a different pharmacokinetic-pharmacodynamic profile, which means that the choice of the drug in practice cannot be accidental. One of the analgesics included in the group of strong opioids is tapentadol, whose mechanism of action is not only related to the interaction with opioid receptors but also depends on the intensification of endogenous processes of descending pain inhibition. Due to the pharmacokinetic and clinical profile of the drug, it can be used with high effectiveness in the treatment of patients with not only nociceptive but also neuropathic pain in various locations.
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