Ophthalmic manifestations of acute leukaemias.

Abstract

To determine the incidence of ocular pathological findings in a group of patients with acute leukemia. To define the predictive value of the presence of the ocular pathological findings. Retrospective evaluation of a group of 67 patients with acute leukemia (age 1-75 years) examined at the Ophthalmology Clinic, Faculty Hospital Ostrava, from 2005 to 2014. Ocular pathological findings were found in 13 patients of the group (19.4 %) - 7 patients with acute myeloid leukemia (10.9 %) and 6 patients with acute lymphoblastic leukemia (8.5 %). 10 patients died due to of the underlying disease. Ocular pathological findings were found in 6 of them (60 %). A higher prognostic value was found in a group of patients with AML. Ophthalmology examination is a necessary part of the examination of patients with acute leukemia. This prognostic benefit is particularly significant in patients with AML. Key words: acute myeloid leukemia, fundus leucaemicus, Roth's spot, ophthalmology examination.