OpenMRE: A Numerical Platform for MRE Study

Abstract

Magnetic resonance elastography (MRE) offers a noninvasive solution to visualize the mechanical properties of soft tissue, but the study suffers from expensive magnetic resonance scanning. Moreover, translating MRE wave images into soft tissue elasticity is a nontrivial issue for clinical professionals and healthcare practitioners. An interactive system-OpenMRE-is thus developed with the aid of ImageJ for numerical MRE study. It is comprised of two comparatively independent toolkits, namely MREA for simulation and MREP for interpretation. MREA mainly deals with the forward problem of MRE, and provides a numerical platform to determine the propagation and distribution of specially designed elastic wave. It is possible to numerically study some state-of-the-art paradigms including multisource and multifrequency MRE. The resultant wave images are interpretable in MREP that is designed for the inverse problem of MRE. It consists of the algorithms for phase unwrapping, directional filtering, and elasticity reconstruction. In a word, OpenMRE offers the MRE community a convenient and well-functioning system for interactive MRE study.