Open-loop analysis of transfer characteristics from blood pressure to heart rate using effectively total artificial heart

Abstract

It is desirable that the dynamic behavior of the drive rate of the artificial heart can be as similar as possible to that of the recipient's heart rate (HR) before implantation. This requires a model which can simulate the behavior of HR on the basis of only information measured with the limited number of approvable sensors. This paper has given a linear time series model for explaining the behavior of HR only with aortic pressure (AOP) and right atrial pressure (RAP). This could be obtained from open-loop analysis using effectively total artificial heart which was introduced for measuring HR in vivo and for eliminating its effect on blood pressure.