Open Trans-Catheter Mitral Valve Replacement for Mitral Annular Calcification

Abstract

Mitral valve replacement in patients with severe mitral annular calcification is a high-risk operation with historically poor outcomes. Percutaneous trans-catheter heart valve (THV) implantation is an alternative therapy to the traditional open surgical approach, but carries significant risks including severe paravalvular leak, left ventricular outflow obstruction, and embolization. To address this, alternative treatment modalities have emerged from the growing experience with THV. Here, we describe an open trans-atrial implantation of a balloon expandable THV. Relative to percutaneous therapies, an open approach permits implanting and expanding the valve under direct visual guidance, with anchoring sutures to precisely position the valve. In comparison to traditional surgical approaches, the risk of left circumflex arterial injury and atrioventricular dissociation is reduced as the annular calcification is left alone and no suture lines are run along the annulus. We illustrate this technique using an Edwards Sapien 3 bioprosthetic valve with an Edwards certitude transthoracic delivery system. Mitral valve replacement in patients with severe mitral annular calcification is a high-risk operation with historically poor outcomes. Percutaneous trans-catheter heart valve (THV) implantation is an alternative therapy to the traditional open surgical approach, but carries significant risks including severe paravalvular leak, left ventricular outflow obstruction, and embolization. To address this, alternative treatment modalities have emerged from the growing experience with THV. Here, we describe an open trans-atrial implantation of a balloon expandable THV. Relative to percutaneous therapies, an open approach permits implanting and expanding the valve under direct visual guidance, with anchoring sutures to precisely position the valve. In comparison to traditional surgical approaches, the risk of left circumflex arterial injury and atrioventricular dissociation is reduced as the annular calcification is left alone and no suture lines are run along the annulus. We illustrate this technique using an Edwards Sapien 3 bioprosthetic valve with an Edwards certitude transthoracic delivery system.