Abstract
Schizencephaly is a rare anomaly of embryonic development characterized by the presence of linear clefts containing cerebrospinal fluid and lined with dysplastic gray matter; which extends from the lateral ventricle to the outer surface of the cortex. The schizencephalic cleft can be open or closed Established etiologies include in-utero infections, young maternal age, abuse of drugs and toxic products. The clinic is dominated by motor impairment, mild mental retardation and epileptic seizures. We report the case of a newborn with macrocrania related to unilateral open cleft schizencephaly.
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