Abstract

A B S T R A C T A data journal in the biomedical field is an innovative task with potential benefits to the scientific society, the pharmaceutical and biotechnology industries, as well as the medical institutions and authorities. It can serve as a source to stimulate, using computational modeling and bioinformatics, the bridging of biomedicine and basic biology researches and connecting pharmaceutical and biotechnology industries with academy. In the era of various high throughput technologies and big data, it could become a powerful driving force to combine expertise to understand the complexity of life and to catalyze new innovative therapeutics and diagnosis. The developments of various high-throughput and/or high-content drugscreening techniques are aiming not only to probe a large number of chemical compounds, but also to obtain deep insights into the molecule/molecule interaction associated with the diversity of chemical space, the structure-activity relationship, as well as the pharmacological mechanism. Moreover, the cellbased drug-screening approaches can shed new light on the dynamics and regulation of proteins and genes associated with various physiological and pathological states.

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