Abstract
ObjectiveAtrial fibrillation (AF) is the most common arrhythmia and it is associated with a five-fold risk of stroke. Atrial fibrillation associated ischaemic strokes and embolisms are more disabling and fatal. We aimed to investigate the time to ischemic stroke/embolism after the diagnosis of AF in patients who never used warfarin.MethodsWe analyzed the records of 402674 patients over the age 18 who had the diagnosis of non-valvular atrial fibrillation (AF) according to ICD-10 code I48 from a nation-wide claims and utilization management system which processes claims for all health insurance funds in Turkey since 2007. In this study we have used completely anonymized data. Time-to-event analysis were used to measure the time to ischemic stroke/embolism after being diagnosed with AF.ResultsA total of 28187 AF patients (7 %) had ischemic stroke or emboli. Time to ischemic stroke and emboli was 61,25±0,05 months from the first diagnosis of AF. Stroke/emboli was observed earlier in the patients with CHA2DS2-VASc score >= 2; mean 60,72±0,06 months. Stroke/emboli was observed in patients with CHA2DS2-VASc score 0 and 1 in mean 65,39±0,11 months and mean 65,02 ±0,09 months respectively.Conclusions ObjectiveAtrial fibrillation (AF) is the most common arrhythmia and it is associated with a five-fold risk of stroke. Atrial fibrillation associated ischaemic strokes and embolisms are more disabling and fatal. We aimed to investigate the time to ischemic stroke/embolism after the diagnosis of AF in patients who never used warfarin. Atrial fibrillation (AF) is the most common arrhythmia and it is associated with a five-fold risk of stroke. Atrial fibrillation associated ischaemic strokes and embolisms are more disabling and fatal. We aimed to investigate the time to ischemic stroke/embolism after the diagnosis of AF in patients who never used warfarin. MethodsWe analyzed the records of 402674 patients over the age 18 who had the diagnosis of non-valvular atrial fibrillation (AF) according to ICD-10 code I48 from a nation-wide claims and utilization management system which processes claims for all health insurance funds in Turkey since 2007. In this study we have used completely anonymized data. Time-to-event analysis were used to measure the time to ischemic stroke/embolism after being diagnosed with AF. We analyzed the records of 402674 patients over the age 18 who had the diagnosis of non-valvular atrial fibrillation (AF) according to ICD-10 code I48 from a nation-wide claims and utilization management system which processes claims for all health insurance funds in Turkey since 2007. In this study we have used completely anonymized data. Time-to-event analysis were used to measure the time to ischemic stroke/embolism after being diagnosed with AF. ResultsA total of 28187 AF patients (7 %) had ischemic stroke or emboli. Time to ischemic stroke and emboli was 61,25±0,05 months from the first diagnosis of AF. Stroke/emboli was observed earlier in the patients with CHA2DS2-VASc score >= 2; mean 60,72±0,06 months. Stroke/emboli was observed in patients with CHA2DS2-VASc score 0 and 1 in mean 65,39±0,11 months and mean 65,02 ±0,09 months respectively. A total of 28187 AF patients (7 %) had ischemic stroke or emboli. Time to ischemic stroke and emboli was 61,25±0,05 months from the first diagnosis of AF. Stroke/emboli was observed earlier in the patients with CHA2DS2-VASc score >= 2; mean 60,72±0,06 months. Stroke/emboli was observed in patients with CHA2DS2-VASc score 0 and 1 in mean 65,39±0,11 months and mean 65,02 ±0,09 months respectively. Conclusions
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