OP24.05: Diagnostic value of sonohysterography in patients in tamoxifen (TAM) therapy for breast cancer

Abstract

Results: Median age of the patients was 43 years (range 23–76 yrs); at final pathology according to pTNM classification 4 pts were at stage pT1A1, 20 pts pT1B1 (4 pN1), 2 pts pT1B2, one patient was pT2A pN1 and 4 pts pT2B, no residual tumor was found in 3 patients. TVUS accuracy for tumor detection was 82,4% even in ten cases of small tumour (less than 1 cm), compared to 80% of MRI. 3 pts were not correctly identified, but received prior neoadjuvant chemotherapy and 1 pts was a pT1A1. Comparing tumour maximum diameter at TVUS and final pathology the exact concordance (millimeters + 20%) was 58,8% in tumours sized more than 20 mm. Parametrial involvement was correctly detected by TVUS with an accuracy of the 95,7%. Tumor intensity of vascularization well correlated to vascular space involvement (73,7%), depth of infiltration (>13,5 mm) and positive lymph node (75%). Conclusions: These results confirm the accuracy of TVUS in presurgical evaluation of small cervical cancers and a possible aid of TVUS in identification of patients at risk who can require an adjuvant treatment. Evaluation of post-cone residual disease is very helpful in conservative treatment programs.