Abstract
Objectives: To assess fetal abnormalities and events leading to third-trimester abortion. Methods: Study population included all parturient women with a singleton pregnancy that underwent termination of pregnancy (TOP) in the third trimester in our institute because of fetal indications between the years 1998–2006. Results: Seven hundred and seventy-seven cases of TOP due to fetal anomalies took place in our center during the study period. Fifty two terminations occurred in the third trimester. thirty four (65.3%) of anomalies were structural, of them 20(58.9%) involved the central nervous system. Genetic indications for third trimester TOP included mostly genetic diseases, unlike aneupluidities in earlier terminations. Routine prenatal care raised suspicion of abnormalities in 22(42.3%) cases and diagnosis was established by additional tests. Abnormal findings were either missed in 4(7.7%) cases or developed later in 11(21.1%) cases. No routine prenatal screening was performed in remaining 15(28.8%) cases. Conclusions: Third-trimester abortion may be obviated by timely screening and scanning in some cases.
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