OP15.03: Prenatal and newborn screening for congenital heart disease

Abstract

To investigate the value of prenatal and postnatal echocardiogram in the diagnosis of congenital heart disease. Pregnant women who were born in the hospital from 2017.1 to 2017.12 were included in the study. The fetal structure was routinely screened during the second trimester. The newborns were screened for congenital heart disease by pulse oximetry and auscultation. The positive ones were examined by neonatal echocardiography. At 42 days postpartum, the returning infants underwent routine auscultationand those who were examined positive were further examined by echocardiography. A total of 13,849 pregnant women were collected during the study. 62 cases of congenital heart disease were found before birth, including 34 cases of severe congenital heart disease and 28 cases of mild congenital heart disease. In the neonatal period, 192 cases of congenital heart disease were found, including 6 cases of severe congenital heart disease and 186 cases of mild congenital heart disease. The incidence of congenital heart disease is 18.3%. The most common severe congenital heart disease is tetralogy of Fallot, a total of 17 cases. The cases of prenatal missed diagnosis were 3 cases of tetralogy of Fallot, 2 cases of total abnormal pulmonary venous drainage and 1 case of transposition of great arteries. The more common congenital heart diseases in the neonatal period were atrial septal defect and ventricular septal defect. Fetal echocardiography is more sensitive to the examination of severe congenital heart disease, and postpartum neonatal echocardiography can detect more mild congenital heart disease. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.