Abstract

Purpose Whereas In most countries cigarette is the most form of tobacco use, in Asia many of smokers use smokeless tobacco (SLT). (SLT) is an addiction resulting in serious health problems including oral cancers. Therefore, it is important to understand the possible consequences on public health. The aim of this review is to evaluate the relation of SLT and oral cancer. Method This review summarizes the findings from studies that addressed the effects of SLT on oral tissue which were published between 2000 and 2012. Result TSNA exposure was much higher with smokeless tobacco than other product use. Several studies showed that association of oropharyngeal cancer with ST use was four times higher relative to no history of tobacco use. In a case-control study of 350 cases and 350 controls reported the frequency of smokeless tobacco in oral cancer cases was significantly higher than controls ( p Conclusion smokeless tobacco has to be controlled along with tobacco smoking. National policies need to take the threat of smokeless of tobacco.

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