Abstract

Objectives: The aim of this retrospective study was to compare the accuracy of 10 commonly used weight estimation formulas in a group of fetuses with extreme macrosomia (≥4.500 g). Methods: Ten different formulas were evaluated in a group of 174 fetuses with a birth weight (BW) ≥4.500 g. Each fetus underwent ultrasound examination with complete biometric parameters within 7 days of delivery. The accuracy of the different formulas for fetal weight estimation (FWE) was compared by mean percentage error (MPE), median of the absolute percentage error (MAPE), the ‘limitsof-agreement’ method and the percentage of FWE falling within the 10% range of the true birth weight. Results: MPE was largest with the Schild formula (MPE −15.43%) and the Shepard formula (MPE 6.08%) and closest to zero with the Hadlock III formula (MPE 5.34%). The MPE of all formulas showed significant bias when compared to zero. All tested formulas, except the Shepard and Shinozuka equations, significantly underestimated fetal weight. The Hadlock III formula obtained the highest percentage of FWE within the 10% range of the true birth weight (66.3%). However, formulas estimated fetal weight in less than two thirds of cases within the 10% range of the true birth weight. Conclusions: Exact weight estimation in extreme macrosomia remains an unsolved problem questioning clinical decisions solely based on ultrasound data.

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