Abstract
centile) 2) Control group (n = 88) included patients whose infants were appropriate for gestational age (birth weight >10th centile). Poor neurodevelopmental outcome was defined as the presence of hearing impairment or severe developmental delay and was compared between the two groups. Results: Primary CMV infection occurred during the first trimester in 5 (33%) of the IUGR cases and 26 (29%) of the control cases (P = 0.8). The mean birth weight in the study group was 2460 gr compared to 3180 gr among the control patients (P < 0.01). The median age of children at follow-up was 2 years (range 3 months–8 years). The rate of poor neurodevelopmental outcome was similar among the two groups: Two (13%) infants in the study group had hearing impairment whereas 8 (9%) of the infants in the control group were diagnosed with hearing impairment (7) or developmental delay (1) on post-natal follow-up (P = 0.6). Conclusions: The outcome of congenital CMV infection does not seem to be affected by the presence of isolated IUGR. Therefore, the prognostic value of IUGR as a sole finding in fetuses infected by CMV is limited.
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