OP0181 Deletion of the prostaglandin D2 receptor DP1 exacerbates aging-associated and instability-induced osteoarthritis

Y Ouhaddi,H Fahmi,L Habouri,J-P Pelletier,J Martel-Pelletier,M Benderdour

doi:10.1136/annrheumdis-2017-eular.6132

OP0181 Deletion of the prostaglandin D2 receptor DP1 exacerbates aging-associated and instability-induced osteoarthritis

Y Ouhaddi, H Fahmi + Show 4 more

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https://doi.org/10.1136/annrheumdis-2017-eular.6132

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Journal: Annals of the Rheumatic Diseases

Publication Date: Jun 1, 2017

#D Prostanoid Receptor 1 #Development Of Osteoarthritis + Show 8 more

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Abstract

BackgroundThe D prostanoid receptor 1 (DP1), a receptor for prostaglandin D2 (PGD2) plays important roles in inflammation and cartilage metabolism. However, its role in the pathogenesis of osteoarthritis (OA) remains...

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