OP-009 The Relationship Between Heart Failure Stage/Symptom Class and Neutrophil to Lymphocyte Ratio

Abstract

BackgroundRecently, neutrophil to lymphocyte ratio (N/L) as showing inflammatory and oxidative stress has been widely studied in various cardiovascular diseases. There is no data regarding the relationship between this parameter and heart failure stage/symptom class.AimThe aim of this study was to evaluate the relationship between N/L and heart failure stages/symptom classes.MethodsA total of consecutive 419 patients with a mean age of 57.9 ± 14.4 years (age range, 18-96 years) admitted with the symptoms of heart failure and/or with risk factors for heart failure were included in the study. Complete blood count was obtained from all study participants to calculate N/L at admission.ResultsTwo hundred and nineteen patients (52.3%) were male, 247 (58.9%) had hypertension, 139 (33.2%) had diabetes, and 248 cases (59.2%) had coronary heart disease. Stage A heart failure was present in 113 patients (27.0%), stage B in 119 patients (28.4%), stage C in 116 patients (27.7%), and stage D in remaining 71 cases (16.9%). With regard to NYHA classification, 228 patients (54.4%) had class I symptoms, 101 (24.1%) had class II symptoms, 31 (7.4%) had class III symptoms, and class IV symptoms were found in remaining 59 patients (14.1%). The mean left ventricular ejection fraction of all population was 54.2% ± 12.4 and the mean N/L was 2.70 ± 1.80. Both heart failure stage and symptom class were found to be significantly and positively associated with N/L (table).ConclusionTable BackgroundRecently, neutrophil to lymphocyte ratio (N/L) as showing inflammatory and oxidative stress has been widely studied in various cardiovascular diseases. There is no data regarding the relationship between this parameter and heart failure stage/symptom class. Recently, neutrophil to lymphocyte ratio (N/L) as showing inflammatory and oxidative stress has been widely studied in various cardiovascular diseases. There is no data regarding the relationship between this parameter and heart failure stage/symptom class. AimThe aim of this study was to evaluate the relationship between N/L and heart failure stages/symptom classes. The aim of this study was to evaluate the relationship between N/L and heart failure stages/symptom classes. MethodsA total of consecutive 419 patients with a mean age of 57.9 ± 14.4 years (age range, 18-96 years) admitted with the symptoms of heart failure and/or with risk factors for heart failure were included in the study. Complete blood count was obtained from all study participants to calculate N/L at admission. A total of consecutive 419 patients with a mean age of 57.9 ± 14.4 years (age range, 18-96 years) admitted with the symptoms of heart failure and/or with risk factors for heart failure were included in the study. Complete blood count was obtained from all study participants to calculate N/L at admission. ResultsTwo hundred and nineteen patients (52.3%) were male, 247 (58.9%) had hypertension, 139 (33.2%) had diabetes, and 248 cases (59.2%) had coronary heart disease. Stage A heart failure was present in 113 patients (27.0%), stage B in 119 patients (28.4%), stage C in 116 patients (27.7%), and stage D in remaining 71 cases (16.9%). With regard to NYHA classification, 228 patients (54.4%) had class I symptoms, 101 (24.1%) had class II symptoms, 31 (7.4%) had class III symptoms, and class IV symptoms were found in remaining 59 patients (14.1%). The mean left ventricular ejection fraction of all population was 54.2% ± 12.4 and the mean N/L was 2.70 ± 1.80. Both heart failure stage and symptom class were found to be significantly and positively associated with N/L (table). Two hundred and nineteen patients (52.3%) were male, 247 (58.9%) had hypertension, 139 (33.2%) had diabetes, and 248 cases (59.2%) had coronary heart disease. Stage A heart failure was present in 113 patients (27.0%), stage B in 119 patients (28.4%), stage C in 116 patients (27.7%), and stage D in remaining 71 cases (16.9%). With regard to NYHA classification, 228 patients (54.4%) had class I symptoms, 101 (24.1%) had class II symptoms, 31 (7.4%) had class III symptoms, and class IV symptoms were found in remaining 59 patients (14.1%). The mean left ventricular ejection fraction of all population was 54.2% ± 12.4 and the mean N/L was 2.70 ± 1.80. Both heart failure stage and symptom class were found to be significantly and positively associated with N/L (table). ConclusionTable