Abstract
Purpose: Doppler tissue imaging (DTI) allows noninvasive assessment of both left ventricular (LV) and right ventricular (RV) function. The aim of this study was to evaluate the effect of hemodialysis (HD) on LV and RV function using DTI. Method: Our study group included 30 patients on chronic HD program (mean age 45 15 years). Myocardial (Sm, Em, Am) and annular velocities (Ea, Aa) were measured in several cardiac territories before and after HD. Results: After HD, Ea significantly reduced from 10.8 3.4 cm/s to 9.6 2.4 cm/s (p = 0.029). Patients exhibited a lower Em following HD in all measured territories. Em/Am ratio was also reduced for each LV wall investigated after HD in all measured territories. At the RV segments, Sm, Em, and Am decreased significantly in all measured territories. Em of the anterior wall was positively related to ultrafiltration volume (r = 0.25, p = 0.006), whereas the decrease of Sm of RV basal segment correlated with a decrease of diastolic blood pressure (r = 0.23, p < 0.01). Conclusion: Our data indicate that a single HD session is associated with acute changes of systolic and diastolic parameters of LV and RV.
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