OP-058: NEUTROPHIL/LYMPHOCYTE RATIO IN PATIENTS WITH NON-DIPPER HYPERTENSION

Abstract

Objective: Heart Transplantation remains excellent long term outcomes with end stage cardiac failure. Pulmonary Hypertension is generally observed in patients with heart failure who are being considered for heart transplantation. Fixed pulmonary hypertension has been associated with a higher risk of early post heart transplant mortality. Fixed pulmonary hypertension is therefore considered as contraindication for heart transplantation. However pulmonary hypertension is reversible in many patients by medications and these patients may be treated by transplantation. We want to discriminate the effects and outcomes of pulmonary hypertension in heart transplantaion. Methods: Data were collected on 28 patients who underwent cardiac transplantation between September 2009 and January 2011. Data collected on recipients include demographics (age, gender), past medical history, echocardiographic pulmonary artery pressure measurement and postoperative hospital mortality and morbidity. Patients whom systolic pulmonary arterial pressure are greater than 45mmHg are accepted as pulmonary hypertension. Results: The follow up period was 30 days postoperatively. Mean age of the patients was 37. Systolic pulmonary arterial pressure was greater than 45mmHg in 7 patients. Hospital Mortality (30 days) for Pulmonary Hypertensive group was 28.5%. Mortality for the non-pulmonary hypertensive group was 9.5%. Mean ICU stay is also implied to be higher in pulmonary hypertensive group. Conclusions: Pulmonary Hypertension is a major risk factor that increase the morbidity and mortality. Decision of surgery should be made in the light of reversibility of the pulmonary pressure and patient’s clinic.