Abstract
Summary Aqueous extracts prepared from thoracic ganglia and ovaries had oostatic activity when injected into the housefly, Musca domestica vicina. The amount of extractable oostatic hormone in the ovary increased linearly during vitellogenesis with the highest levels occurring in the post-vitellogenic ovary. The oostatic hormone content in the thoracic ganglia fiom flies of different ages fit a parabolic curve with higher levels at emergence and 72 h and lower levels at 36 and 48 h. Aedes aegypti trypsin modulating oostatic factor (TMOF) had oostatic activity when injected into Musca domestica vicina. TMOF antibody reacted with ovarian and thoracic ganglion extracts in dot-ELISA assays. Neurosecretory cells in the periphery of the thoracic ganglion reacted with TMOF antibody.
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