Abstract

Immature oocytes account for 15% of all oocytes collected and are usually discarded during IVF. There is little information on the aneuploidy frequency of in vitro matured (IVM) oocytes derived from young fertile women, and a standardized protocol enabling effective IVM is lacking. Our study aimed to: 1. Assess whether the addition of autologous cumulus cells (CCs) improves IVM rates; 2. Perform a comprehensive analysis of aneuploidy frequency and type in oocytes cultured in the presence or absence of autologous cumulus cells (CCs) during IVM.

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