Abstract
To compare oocyte cryopreservation cycles performed in cancer patients to those of infertile women. Cancer patients referred for fertility preservation underwent counseling in compliance with the ASRM; those electing oocyte cryopreservation were included. Ovarian stimulation was achieved with injectable gonadotropins and freezing was performed using slow-cooling and vitrification methods. Fifty cancer patients (mean age 31y) underwent oocyte cryopreservation; adequate ovarian stimulation was achieved in 10 ± 0.3days. The outcome from these cycles included a mean peak estradiol of 2,376pg/ml and an average of 19 oocytes retrieved (15 mature oocytes were cryopreserved/cycle). All patients tolerated ovarian hyperstimulation. There were no significant differences noted between cryopreservation cycles performed in cancer patients and in women without malignancy. Oocyte cryopreservation appears to be a feasible fertility preservation method for reproductive-age women diagnosed with cancer. This modality is not only effective but also, providing a multidiscipline effort, can be completed in timely fashion.
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